Details
Comprehensive Bioactive Natural Products (Structural Modifications And Drug Development)
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549,99 € |
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| Verlag: | Studium Press |
| Format: | EPUB |
| Veröffentl.: | 30.06.2010 |
| ISBN/EAN: | 9781626993488 |
| Sprache: | englisch |
| Anzahl Seiten: | 335 |
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Beschreibungen
<span>Nature has been providing products that have implications as pharmacological agents. There is even a traditional belief that all the plants grown on this planet have some or other therapeutic/physiological attributes. Natural products isolated in original form are often not fit for their use in human or animal medicine. Sometimes they don't have the required potency and sometimes desired level of biological activity. But, the activities of natural products can be optimized to a desired level by subjecting them to some simpler and logical modifications for their probable use. Recent years have experienced a resurgence of natural products for drug discovery in favor of synthetic drugs. Therefore, it is high time to focus on the world of natural products and find ways, which may be the synthetic modifications of the existing molecules or finding the new molecules to have new drugs which are far more potent and safer to use. The active natural molecules can also serve as starting point for the target based studies and consequently lead to development of new therapeutic agents. </span>
<span>Dr. Vijay Kumar Gupta, Ph.D., FLS, London (born1953-) Deputy Director & Head, Animal House, Indian Institute of Integrative Medicine (CSIR),Jammu, India. He did his M.Sc. (1975) and Ph.D.(1979) in Zoology both from University of Jammu, Jammu-India. His research capabilities are substantiated by his excellent work on histopathology, ecology and reproductive biology offishes, turtles, birds and mammals, which has already got recognition in India and abroad. Dr.Gupta has to his credit more than 75 scientific publications and review articles which have appeared in internationally recognized Indian and foreign journals. Founder fellow, life member and office bearer of many national societies, academies and associations. He has successfully completed a number of research/consultancy projects funded by various governments, private and multinational agencies. His current areas of interest are histopathology, toxicology, pre-clinical safety pharmacology and reproductive efficacy studies of laboratory animals. He is also Editor-in-chief of the books 1) Utilisation and Management of Medicinal Plants 2) Medicinal Plants: Phytochemistry, Pharmacology and Therapeutics 3) Perspectives in Animal Ecology and Reproduction (Vols.1-6). The Editor-in-chief of the American Biographical Institute, USA, has appointed him as Consulting Editor ofThe Contemporary Who's Who. Dr. Gupta also appointed as Nominee for the Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA, Govt. of India). Recently the Linnaean Society of London, U.K. has awarded fellowship to him in November 2009 in recognition of his contribution towards the cultivation of knowledge in Science of Natural History. </span>
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<span>Dr. Subhash Chandra Taneja (born 1950-) obtained his masters degree in Organic Chemistry in 1971 and thereafter completed Ph.D. in Birla Institute of Technology & Science, Pilani, India in 1975 under the guidance of Prof. H.P. Tiwari. He is scientist of eminence and presently working as Scientist 'G', Indian Institute of Integrative Medicine (CSIR), Jammu. Dr. Taneja has over 100 publications in international journals,two book chapters and two review articles, 38 patents of which 14 are USP. He has also visited Institute of Organic Chemistry, Warsaw, Poland(1989-1990) under CSIR Scientist Exchange Programme. His areas of interest are chemistry and bioactivities of medicinal plants and generation of semi-synthetic libraries based on natural product scaffolds; design and synthesis of bioactive lead molecules in the area of inflammation, oncology,infectious diseases, immunomodulation; exploitation of microbial biodiversity for the identification newer sources of biocatalysts e.g. lipases, esterases,glucosidases, nitrilases, oxido-reductases etc. and development of new throughput screening techniques; synthesis and kinetic resolution of important dugs/intermediates using chemo-enzymatic methods; development of green methodologies for the synthesis of mono terpenes and perfumery molecules; development of new glycosylation methodologies; C- and Oglycosylation techniques; new synthetic protection-deprotection methodologies for carbohydrates, and their conversion to bioactive molecules and organic synthesis of natural products and bioactive molecules.</span>
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<span>Dr. Subhash Chandra Taneja (born 1950-) obtained his masters degree in Organic Chemistry in 1971 and thereafter completed Ph.D. in Birla Institute of Technology & Science, Pilani, India in 1975 under the guidance of Prof. H.P. Tiwari. He is scientist of eminence and presently working as Scientist 'G', Indian Institute of Integrative Medicine (CSIR), Jammu. Dr. Taneja has over 100 publications in international journals,two book chapters and two review articles, 38 patents of which 14 are USP. He has also visited Institute of Organic Chemistry, Warsaw, Poland(1989-1990) under CSIR Scientist Exchange Programme. His areas of interest are chemistry and bioactivities of medicinal plants and generation of semi-synthetic libraries based on natural product scaffolds; design and synthesis of bioactive lead molecules in the area of inflammation, oncology,infectious diseases, immunomodulation; exploitation of microbial biodiversity for the identification newer sources of biocatalysts e.g. lipases, esterases,glucosidases, nitrilases, oxido-reductases etc. and development of new throughput screening techniques; synthesis and kinetic resolution of important dugs/intermediates using chemo-enzymatic methods; development of green methodologies for the synthesis of mono terpenes and perfumery molecules; development of new glycosylation methodologies; C- and Oglycosylation techniques; new synthetic protection-deprotection methodologies for carbohydrates, and their conversion to bioactive molecules and organic synthesis of natural products and bioactive molecules.</span>
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