Details

Nanobiomedicine (Nanopharmaceuticals)


Nanobiomedicine (Nanopharmaceuticals)



von: Bhupinder Singh, Kamalinder K Singh

549,99 €

Verlag: Studium Press
Format: EPUB
Veröffentl.: 30.06.2015
ISBN/EAN: 9781626991330
Sprache: englisch
Anzahl Seiten: 540

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Beschreibungen

<span>Nanopharmaceuticals, designing and engineering nanoscale active drugs, drug products and drug delivery systems, is considered to be amongst the frontier technologies of the 21st century. Envisioned to bring revolutionary advances in the diagnosis and treatment of diseases, it represents an emerging area that has distinct potential to overcome long standing problem of low drug bioavailability at the targeted disease site. This volume provides a systematic coverage of the fundamentals, technologies and applications of nanotechnology, currently being employed to foster the development of various pharmaceutical dosage forms and drug delivery systems. Endeavored towards improving the new chemical entities (NCEs) with poor biopharmaceutical properties (i.e., BCS II/IV), this book illustrates several approaches of nanotechnology in drug discovery - employing modeling techniques for pharmaceutical optimization, designing and manufacturing pharmaceutical cocrystals and nanocrystals, and transforming the stabilization characteristics to achieve desirable pharmacokinetic and toxicological attributes. Topics covered range from natural biomaterials, novel carriers, process scale-up, and Design of Experiments under the new paradigm of pharmaceutical Quality by Design (QbD). Use of pharmacokinetic modeling and chronopharmacokinetics for nano-based drug delivery technologies is discussed quite aptly. Applications of nanotechnology in oral, parenteral, transmucosal drug delivery, and in developing nanocosmetics and phytomedicines have been thoroughly overviewed. This book will serve as an important reference for professionals, academicians and students engaged in all facets of drug product development.</span>
<span>Professor Bhupinder Singh Bhoop is globally acclaimed for his research on novel and nanostructured drug delivery using Quality by Design (QbD) paradigms, he has contributed over three decades of dedicated service towards Pharmaceutical Education and Research. His work primarily focuses on lipidic nanostructured systems like SNEDDS (liquid, solid, supersaturable and eutectic), solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), nanoemulsions and mixed nanomicelles, polymeric nanoparticles, functionalized CNTs, and nanovesicular systems like liposomes, niosomes, ethosomes, transfersomes and bilosomes. He has to his credit over 215 publications including 9 books and 33 book chapters. More than 225 keynotes and invited talks have been delivered by him at prestigious forums in various countries. He has organized several Conferences and Symposia including International Conferences, NanoSciTech 2012 &amp; 2014. He has handled 15 research projects and guided/guiding 27 PhD, 4 post-doctorates and over 50 postgraduate scholars. He has completed over a dozen consultancy assignments and industrial projects, has 4 patents and key involvement in tech. transfers of three nano-based drug delivery products. He has duly trained several hundreds of industrial scientists under his guidance esp. QbD of nanostructured systems. His work has fetched him several awards and accolades like, Leading Educators of World (UK) 2007, Pharma Buzz Pharma Personality Award 2008, Shiksha Rattan Award 2008, Innovative Scientist Award 2012, Pharma QbD Excellence Award 2012 by CPhI-Asia, QbD Product Performance Award 2012 and 2013 by Amer Assoc Pharm Sci, USA, Outstanding Scientist Award 2014 by Select Biosciences, UK, PUTA Excellence Award 2014, and StatEase QbD Performance Award 2014, USA. Currently, he is the Chairman of University Institute of Pharmaceutical Sciences, and the Coordinator of UGC Centre of Advanced Studies (CAS) in Pharmaceutical Sciences. Since 2011, he has also been serving as the Founder Coordinator of UGC Centre for Excellence in Nano Applications (Biomedical Sciences). Besides, he has also been the Dean, Faculty of Pharmaceutical Sciences, Panjab University, Chandigarh (2012-14) and Dean Alumni Relations, Panjab University (2007-2011). On the basis of his exemplary accomplishments, the Vice President of India has nominated him to the Senate of Panjab University as its Fellow. E-mail: bsbhoop@yahoo.com, bsbhoop@pu.ac.in </span>
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<span>Dr Kamalinder K Singh is currently a Professor of Pharmaceutical Technology and Drug Delivery, School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, UK, and holds lien from SNDT Women’s University, Mumbai, India where she is Principal &amp; Professor of Pharmaceutics. Her research efforts focus primarily on drug delivery systems, i.e., protein-based nanoparticles, lipid nanostructures, nanosuspensions, microspheres and long acting parenterals. These drug delivery methods are being applied to a variety of diseases including malaria, cancer and dermatological conditions. She also has research interest in the development of novel herbal drug delivery systems. Professor Singh has been bestowed with State Teacher Award 2010-2011 by Maharashtra Government, India, “Manju Pal Best Pharmaceutical Scientist Award 2012” and “Pharmacy Teacher of the Year Award 2008”, for outstanding contribution to pharmacy education and research by Association of Pharmaceutical Teachers of India (APTI), and “Outstanding Herbal Formulator” by Aromatic Plants Board 2008. She serves on International Steering Committee for “Handbook of Pharmaceutical Excipients”, joint publication by AAPS, Pharmaceutical Press, and Royal Pharmaceutical Society, Great Britain. She has contributed 5 monographs in the 5th edition (2005), 10 monographs in the 6th edition (2009), and 15 monographs for the 7th edition (2013) of this book. She has also authored 7 book chapters and 52 research publications. She has made over 250 research presentations and over 50 invited lectures at scientific meetings and conferences. She has supervised over 60 research students. Professor Singh has been Scientific Chair (2011-13), Vice president (2011-13) and Secretary (2007-2011) of Indian Chapter of Controlled release Society. She has served on the various academic bodies of SNDT Women’s University including Senate, academic council, BCUD and Chair of Pharmacy Board. Based on her research work, Professor Singh has filed 13 patents out of which one US and four Indian patents have already been granted. E-mail: ksingh1@uclan.ac.uk, kksingh35@ hotmail.com </span>

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