Details
Nanobiomedicine (Nanotheranostics)
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549,99 € |
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| Verlag: | Studium Press |
| Format: | EPUB |
| Veröffentl.: | 30.06.2015 |
| ISBN/EAN: | 9781626991347 |
| Sprache: | englisch |
| Anzahl Seiten: | 456 |
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Beschreibungen
<span>Theranostics, a harmonious merger of therapeutics and diagnostics, paves the path to personalized medicine. Theranostics plays a crucial role in steering every step of drug development process, primarily the biomarker discovery, target selection and validation of biomarkers, dose optimization and monitoring of the drug response. This book - a compilation of current status of the burgeoning progress in the field of nanotheranostics - presents multidisciplinary chapters focusing on advanced techniques for imaging, including the in vivo multimodal imaging of tumors, drug delivery, diagnosis and site-specific targeting. The book delineates the applications of different types of nanostructures, viz. liposomes, polymer-based nanoparticles, solid lipid nanoparticles, ceramic-based nanoparticles, albumin nanoparticles, superparamagnetic iron oxide nanoparticles, semiconductor nanoparticles, dendrimers, silica-based nanocomposites and carbon nanotubes in drug delivery and as novel theranostic systems. It also focuses on metallic nanoparticles such as gold nanorods-based contrast agents for optoacoustic tomography, photothermal therapy and preclinical investigations. Further, the advent of metallo-fullerenes and nano-shells, the most recently developed metallic nanoparticles, as newer strategies employed in the treatment of various cancers and as theranostics agents, is aptly described. Use of novel neurological models, proteomic-based biomarker identification for cancer diagnostics and the futuristic applications of nanoparticles as platforms for theranostics, consisting of nucelic acid-based therapies in dermatology, radiolabeling nanoparticles for in vivo molecular imaging and nuclear scintigraphy, are presented in this volume too. This book is an elaborated treatise for researchers, young and experienced both, to relish and savor the current status of theranostics and its various applications available today and imminent in the near future.</span>
<span>Professor Bhupinder Singh Bhoop is globally acclaimed for his research on novel and nanostructured drug delivery using Quality by Design (QbD) paradigms, he has contributed over three decades of dedicated service towards Pharmaceutical Education and Research. His work primarily focuses on lipidic nanostructured systems like SNEDDS (liquid, solid, supersaturable and eutectic), solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), nanoemulsions and mixed nanomicelles, polymeric nanoparticles, functionalized CNTs, and nanovesicular systems like liposomes, niosomes, ethosomes, transfersomes and bilosomes. He has to his credit over 215 publications including 9 books and 33 book chapters. More than 225 keynotes and invited talks have been delivered by him at prestigious forums in various countries. He has organized several Conferences and Symposia including International Conferences, NanoSciTech 2012 & 2014. He has handled 15 research projects and guided/guiding 27 PhD, 4 post-doctorates and over 50 postgraduate scholars. He has completed over a dozen consultancy assignments and industrial projects, has 4 patents and key involvement in tech. transfers of three nano-based drug delivery products. He has duly trained several hundreds of industrial scientists under his guidance esp. QbD of nanostructured systems. His work has fetched him several awards and accolades like, Leading Educators of World (UK) 2007, Pharma Buzz Pharma Personality Award 2008, Shiksha Rattan Award 2008, Innovative Scientist Award 2012, Pharma QbD Excellence Award 2012 by CPhI-Asia, QbD Product Performance Award 2012 and 2013 by Amer Assoc Pharm Sci, USA, Outstanding Scientist Award 2014 by Select Biosciences, UK, PUTA Excellence Award 2014, and StatEase QbD Performance Award 2014, USA. Currently, he is the Chairman of University Institute of Pharmaceutical Sciences, and the Coordinator of UGC Centre of Advanced Studies (CAS) in Pharmaceutical Sciences. Since 2011, he has also been serving as the Founder Coordinator of UGC Centre for Excellence in Nano Applications (Biomedical Sciences). Besides, he has also been the Dean, Faculty of Pharmaceutical Sciences, Panjab University, Chandigarh (2012-14) and Dean Alumni Relations, Panjab University (2007-2011). On the basis of his exemplary accomplishments, the Vice President of India has nominated him to the Senate of Panjab University as its Fellow. E-mail: bsbhoop@yahoo.com, bsbhoop@pu.ac.in </span>
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<span>Dr Mandip Sachdeva is a Professor of Pharmaceutics, and the Section Leader at College of Pharmacy, Florida A&M University, USA. Dr Sachdeva has made significant contribution in the areas of formulation development, drug delivery and protein delivery via inhalation, topical and parenteral route of administration for various pathological disorders such as lung cancer, breast cancer and skin diseases, and in the area of bioimaging. He has worked on diverse nanostructured drug delivery systems including liposomes, niosomes and various nano-lipidic carrier systems to deliver, drugs, peptides, siRNA, shRNA, etc. He has consistently been funded by NASA, Department of Defense and NIH by over 25 million US dollars in the last two decades, and has also worked on several company contracts. Presently, he has over 117 peer-reviewed publications and 8 book chapters to his credit. Very widely travelled researcher, he has over 200 invited talks and around 190 presentations in national and international scientific conferences and meetings. He has also been granted 5 patents and several more have been filed. He has mentored over 20 MS/Ph D students and trained 21 post-doctoral fellows. Recipient of the Davis Productivity Award from the State of Florida, Dr Sachdeva has received numerous research achievement awards from Florida A&M University too. A Fellow of the AAPS (2009), he was recently granted a Fulbright Fellow Award. Since 2005, he has been the Editor-in-Chief of CRC Critical Reviews in Therapeutic Drug Carrier Systems, and serves on Editorial Board of several international journals. He has also organized 8 International Symposia. Currently, he is exploring approaches to treat lung and triple negative breast cancer, UV-B induced skin carcinogenesis, keratrolytic lipids for delivering siRNA or shRNAs for skin inflammation, surface modified nanoparticles with various ligands, enhancing delivering of nanoparticles by modifying the tumor microenvironment and in developing imaging techniques to track nanoparticles in tumors and skin layers. E-mail: mandip.sachdeva@ gmail.com, mandip.sachdeva@famu.edu</span>
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<span>Dr Mandip Sachdeva is a Professor of Pharmaceutics, and the Section Leader at College of Pharmacy, Florida A&M University, USA. Dr Sachdeva has made significant contribution in the areas of formulation development, drug delivery and protein delivery via inhalation, topical and parenteral route of administration for various pathological disorders such as lung cancer, breast cancer and skin diseases, and in the area of bioimaging. He has worked on diverse nanostructured drug delivery systems including liposomes, niosomes and various nano-lipidic carrier systems to deliver, drugs, peptides, siRNA, shRNA, etc. He has consistently been funded by NASA, Department of Defense and NIH by over 25 million US dollars in the last two decades, and has also worked on several company contracts. Presently, he has over 117 peer-reviewed publications and 8 book chapters to his credit. Very widely travelled researcher, he has over 200 invited talks and around 190 presentations in national and international scientific conferences and meetings. He has also been granted 5 patents and several more have been filed. He has mentored over 20 MS/Ph D students and trained 21 post-doctoral fellows. Recipient of the Davis Productivity Award from the State of Florida, Dr Sachdeva has received numerous research achievement awards from Florida A&M University too. A Fellow of the AAPS (2009), he was recently granted a Fulbright Fellow Award. Since 2005, he has been the Editor-in-Chief of CRC Critical Reviews in Therapeutic Drug Carrier Systems, and serves on Editorial Board of several international journals. He has also organized 8 International Symposia. Currently, he is exploring approaches to treat lung and triple negative breast cancer, UV-B induced skin carcinogenesis, keratrolytic lipids for delivering siRNA or shRNAs for skin inflammation, surface modified nanoparticles with various ligands, enhancing delivering of nanoparticles by modifying the tumor microenvironment and in developing imaging techniques to track nanoparticles in tumors and skin layers. E-mail: mandip.sachdeva@ gmail.com, mandip.sachdeva@famu.edu</span>
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